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INTERNATIONAL: Internet addiction: Are we valuing the virtual over reality?

Drug News Bot - Thu, 08/03/2017 - 00:03
irishtimes.com (Europe) Internet addiction: Are we valuing the virtual over reality? b If we are not all clinically addicted per se. (Thu Aug 03 01:03:22 2017 PDT) [$drug_related(60%), $drugwar_propaganda(100%), $propaganda_theme1(60%), $addiction(60%), $propaganda_theme2(80%), $propaganda_theme3(55%), $gateway(60%), $propaganda_theme4(60%), $propaganda_theme5(100%), $propaganda_theme7(80%), $moral_imperative(100%), $illegal_drugs(60%), $youth(100%)]
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TOP: Illinois approves 1st medical marijuana workers to grow legal pot - Chicago Tribune

Bot - Cannabis - Thu, 08/03/2017 - 00:01
chicagotribune.com (US) Should start growing soon Sunlight streaming through a glass roof in a rural warehouse will likely soon be feeding one of Illinois' first legal crops of marijuana seedlings. Once that is secured. Along with IDs for workers who have passed background checks. (Thu Aug 03 14:01:47 2017 PDT)
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TOP: Tribune reports: Medical marijuana comes to Illinois - Chicago Tribune

Bot - Cannabis - Thu, 08/03/2017 - 00:01
chicagotribune.com (US) Who is selling it. Who is using it and why. Medical pot for PTSD could save program Advocates for medical marijuana hope Illinois' plan to expand its program will give the industry the boost it needs to sustain itself b but some doctors warn that. (Thu Aug 03 14:01:47 2017 PDT)
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Booker Debuts 'Marijuana Justice Act' to Legalize Cannabis - Leafly

Google - Cannabis - Wed, 08/02/2017 - 21:47

Leafly

Booker Debuts 'Marijuana Justice Act' to Legalize Cannabis
Leafly
The Marijuana Justice Act creates incentives for states to change their cannabis laws and stop enforcing existing laws in an unjust manner. It also includes mechanisms for people incarcerated for marijuana crimes to appeal to the courts to have their ...
'Marijuana Justice Act' Would End Weed Prohibition Throughout The LandForbes
US Marijuana Act Seeks to Legalize Marijuana at Federal LevelteleSUR English
Sen. Cory Booker just introduced a bill that could legalize marijuana nationwideVox
Newsweek -TIME -NJ.com -Facebook
all 200 news articles »
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Stock-trading policy change looms over cannabis industry - The Globe and Mail

Google - Cannabis - Wed, 08/02/2017 - 18:02

The Globe and Mail

Stock-trading policy change looms over cannabis industry
The Globe and Mail
... Canada's major stock-exchange operator is considering a move that would make it difficult for investors to trade the shares of cannabis companies with U.S. assets, potentially disrupting the flow of millions of dollars into the burgeoning marijuana ...

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London cop fired after turning up to work high on cannabis despite claiming it didn't affect his work - The Sun

Google - Cannabis - Wed, 08/02/2017 - 16:12

The Sun

London cop fired after turning up to work high on cannabis despite claiming it didn't affect his work
The Sun
Bosses noticed Met PC Lee Colbridge was behaving strangely when he arrived in Camden, North London, at 8am. Met PC Lee Colbridge has been sacked after turning up to work high on cannabis. Alamy. 2. Met PC Lee Colbridge has been sacked after ...

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Cannabis and Meditation: Best Practices for an Elevated Mind - Leafly

Google - Cannabis - Wed, 08/02/2017 - 15:32

Leafly

Cannabis and Meditation: Best Practices for an Elevated Mind
Leafly
Cannabis has a knack for focusing the mind when combined with meditation techniques, and with our guide below, it won't be long before meditation is a simple part of your daily health regime. With time, patience, and perseverance, you'll go from ...

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Putting the Stank in the Dank: 5 Really Foul-Smelling Marijuana Strains

Alternet - Wed, 08/02/2017 - 13:36
Click here for reuse options! Who cut the cheese?

Smell is typically a selling point for pot aficionados. Whether it’s the piney scent of a nice Northern Lights-based bud, the fruity berry aroma of strains like Blue Dream, or the lemon-limey scent of Diesel-based strains, smell sells.

But not all pot smells pleasant. There are some strains that exude a downright funky aroma, others whose scent can only be called "strange," and yet others that just stink up the joint. Yet, oddly enough, foul-smelling strains still sell. They wouldn't be in the marketplace otherwise. Here, courtesy of the pursuers of all things marijuana over at Leafly, are five of the nastiest. 

1. Sour Cheese. Like sharp cheddar gone bad, the Cheese strains (also including UK Cheese and Exodus Cheese) have a sour, savory scent. Still, the hybrids' mellow euphoria and energy-lift makes it sought after despite the stink. Leafly readers were divided:

“When you open the jar and take a whiff you are greeted with a splash of pungent sour that quickly turns into a smooth cheese. The buds release a satisfying snap that throws trichomes into the air when broken from the stems.” – Neemix

 “Smells like puke.” – soop21 opined concisely.

2. Cat Piss. This pungent sativa produces an ammonia-like odor, thus the name. But for some users, the plant's stimulating buzz overcomes its cat box ambience. Here's what Leafly reviewers had to say:

 “Besides the [wretched] taste that leaves you wanting water and a mint, soon you will be too uplifted to care! Effects are amazing and are long lasting.” –misterbest

 “Yuck. It really does smell like cat piss. Strong, racy sativa. Made me paranoid.” –aarvind

3. Dog Shit. Now there's a strain name that just screams out "Buy me!" Yet despite the off-putting moniker, Dog Shit sells, too. Fortunately for the rest of us, this stinky hybrid is found mainly in Oregon, where it has picked up both fans and foes among Leafly reviewers:

 “My first impressions of the bud were that they were very stinky and definitely lived up to their name however once I smoked it the smell evolved into something more sweet and pleasant.” – DogeKing

“I got very anxious and paranoid when taking this and it smells kinda bad.” – BONECRUSHER27

 4. M-39. Is this stuff grown in the Alberta oil sands? This Canadian strain is likened to "ditchweed grown in a tar pit" by Leafly. It is a popular Canadian strain, though, with some arguing that its dull aroma makes it easier to smuggle. Again, Leafly reviewer opinion is divided:

“It has a very strong smell almost a combination of paint and smelly body odor.” – StoneySundays

 “[H]as a soft smoke with notes of peanut butter and fall aroma.” – ray8753

 5. Grandpa’s Breath. This strain has a hint of must to it, but the name actually derives from its genetics: It is descended from the famous Granddaddy Purple. Probably not as off-putting as some of the other strains on this list, but the name itself can set sensory expectations. Again, one man's poison is another man's pleasure:

 “Real nice body high, heavy relaxed head feeling, taste isn’t amazing but isn’t unpleasant either.” – hazefordayz

 “This is one of the best tasting and medicating, fragrant strains I’ve ever had. I looooove Grandpa’s Breath!” – Strandz

If you're looking for the dank with the stank, here you go. 

 

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Officials Grapple With Limiting Cannabis Ads at Las Vegas Airport - Leafly

Google - Cannabis - Wed, 08/02/2017 - 12:57

Leafly

Officials Grapple With Limiting Cannabis Ads at Las Vegas Airport
Leafly
LAS VEGAS (AP) — Officials are grappling with how to limit advertisements for marijuana at Las Vegas' McCarran International Airport. Clark County commissioners on Tuesday discussed a proposed ordinance that would ban cannabis ads at the airport.

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Heavy Interest in North Dakota Medical Marijuana Network - Leafly

Google - Cannabis - Wed, 08/02/2017 - 11:13

Leafly

Heavy Interest in North Dakota Medical Marijuana Network
Leafly
North Dakota voters last November approved medical cannabis, and the Legislature earlier this year crafted regulations that Gov. Doug Burgum approved in April. The North Dakota Compassionate Care Act allows the use of medical marijuana to treat 17 ...

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Doctor Murdered for NOT Prescribing Opioids

Alternet - Wed, 08/02/2017 - 10:21
The doctor was shot in a hospital parking lot by the enraged spouse of a chronic pain patient.

Authorities are investigating the murder of a doctor in northern Indiana, who was shot to death for not prescribing opioid medication.

It’s yet unknown which specific medication the patient, Petra Jarvis, was seeking at her appointment last Wednesday (July 26), but Dr. Todd Graham’s refusal to write a prescription for her chronic pain was apparently enough for her husband, Michael Jarvis, to seek revenge. 

Two hours after his wife’s appointment, Jarvis went looking for Dr. Graham and shot him twice in the parking lot of St. Joseph Rehabilitation Institute, a clinic in Mishawaka.

“He did what we ask our doctors to do. Don’t overprescribe opioids,” said St. Joseph County Prosecutor Ken Cotter at a press conference. “Unfortunately, for whatever reason, Jarvis made that choice to take his life.”

After killing the doctor, the disgruntled husband then drove to his friend’s home about three miles away, reported the South Bend Tribune. But when Jarvis “gave them indication that he was not going to be around,” his friend, concerned, called the police. 

By the time the authorities arrived, however, Jarvis had shot and killed himself outside the home. Authorities are puzzled by the murder-suicide and how opioids factor into the tragedy.

“Make no mistake, this is a person who made a choice to kill Dr. Graham,” said Cotter. “This is not a fallout from the opioid epidemic or any opioid problems. That probably leads us into an examination of what is happening with the opioid problem in our community, and frankly, our whole nation.”

Cotter says investigators are looking at the couple’s medication history and Jarvis’s mental state prior to his death, since clearly he “may have also had his own issues.” 

“We’re talking about a man who made a choice to kill another person,” said Cotter. 

They have yet to determine if opioid addiction had anything to do with it. “Was that a contributing factor in his decision? We don’t know that yet,” said the prosecutor.

memorial service for Dr. Graham, who was 56, was held at St. Pius X Catholic Church in nearby Granger on Monday.

“Every homicide is tragic, but this one in particular, I think, hits home to everyone,” said Cotter. “[A doctor’s] job is to try to help people, and that [was] certainly what Dr. Graham was doing.”

 

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The Cutting Edge of Marijuana Medical Research Will Leave You Wondering What It Can't Help Cure

Alternet - Wed, 08/02/2017 - 09:59
New findings highlight CBD’s therapeutic potential for cancer, epilepsy, Alzheimer’s, high blood pressure, and other disorders.

During the last week of June, more than 400 scientists from 25 countries met in Montreal for the 27th annual symposium of the International Cannabinoid Research Society (ICRS). Several presentations and posters showcased new findings about cannabidiol (CBD), the non-euphoric component of the cannabis plant that is transforming the medical marijuana landscape.

In her Young Investigator Award Presentation, Saoirse O’Sullivan, associate professor at the University of Nottingham in the United Kingdom, discussed the cardiovascular effects of cannabidiol: “CBD causes both acute and time dependent vasorelaxation of rat and human arteries … and can improve endothelial function and vasodilator responses in a rat model of type 2 diabetes.” Moreover, a single dose of CBD was found to decrease “resting blood pressure and the blood pressure response to stress.” Other studies indicate that CBD limits brain damage in animal models of stroke. “Collectively, these data suggest that CBD is a compound of interest in the cardiovascular system and in cardiovascular disorders, which need to be tested in relevant patient groups,” O’Sullivan concluded.

A poster by Dr. Paula B. Dall’Stella, a neuro-oncologist with Sirio Libanes Hospital in San Paulo, Brazil, documented the antitumoral effects of CBD in two patients with Glioblastoma Multiforme (brain cancer) that were resistant to other therapies. Before and after MRI scans showed “a marked remission … not commonly observed in patients only treated with conventional modalities … that could impact survival.”

Several presentations focused on CBD and treatment-resistant epilepsy. Dr. Fabricio A. Pamplona, scientific director of of Entourage Phytolab in San Paulo, Brazil, compared the efficacy of a purified CBDisolate to a whole plant CBD-rich oil extract. Pamplona found the whole plant extract to be a superior option with higher potency and fewer adverse side effects than single-molecule CBD: “There were more reports of ‘improvement in seizures frequency’ in CBD-enriched extract compared to purified CBD,” a result that he attributed to the “additional compounds available in extracts (other than CBD) that may interact synergistically.”

Israeli researchers at the Technion institute in Haifa found that “not all high CBD extracts have the same anticonvulsant ability.” The Israelis noted that “the terpenoid content in the cannabis extracts are important for the anticonvulsant effect.” (Terpenoids are derived from terpenes, the aromatic botanical compounds that endow cannabis with a unique smell and confer specific medicinal effects.) “Not all cannabis extracts will be useful as a treatment for epilepsy,” the Technion researchers concluded, adding: “[T]he exact cannabinoid and terpenoid profiles are needed to evaluate the potential anticonvulsant properties of a cannabis extract.”

Another poster drew attention to the fact that daily use of CBD-rich cannabis oil extracts may lead to a positive THC finding in a drug test, a concern for many U.S. patients in so-called “CBD-only states” that have legalized CBD but not the whole plant. Unfortunately, this poster resurrected the thoroughly discredited (and financially motivated) theory that CBD may convert to THC in the stomach. A more likely explanation is that any whole cannabis plant extract that includes even a small amount of THC could generate a positive result from a drug test. Given the unregulated CBD products that proliferate online, it’s not surprising that some “CBD” oils contain higher THC concentrations than advertised.

Other scientists probed CBD’s mechanism of action with respect to nausea, neuropathic pain, anxiety, and other mood disorders. Researchers at McGill University in Montreal found that analgesic effects of acute and chronic CBD treatment are mediated by the serotonin 5HT1a receptor, but this is not the case for CBD’s antidepressant effects, which seem to be regulated via other molecular pathways.

The complex role of the 5HT1a receptor with respect to CBD’s therapeutic properties was addressed in a poster by Aidan J. Hampson and his colleagues at the National Institute of Drug Abuse. It was Hampson’s work, published in 1998, that formed that basis for the U.S. government’s patent on the antioxidant and neuroprotectant properties of cannabinoids (both THC and CBD). More recently, Hampson has shown that the anxiety-relieving effect of CBD can be blocked in vivo (in a living animal) by a 5HT1a antagonist, indicating that this receptor is in part responsible for mediating the anxiolytic effects of cannabidiol. Curiously, Hampson’s current data suggests that in addition to binding directly to 5HT1a, cannabidiol may also act as a positive allosteric modulator of 5HT1a – meaning that CBD can alter the functionality of this receptor (and other serotonin receptor subtypes) in such a way as to enhance its binding efficiency with the endogenous serotonin neurotransmitter. In other words, CBD may actually magnify the effect of serotonin, in addition to directly activating the 5HT1a receptor.

Scientists at the University of Louisville School of Medicine in Kentucky have identified two new molecular targets of CBD – the receptors designated “GPR3” and “GPR6.” (GPR refers to G-coupled protein receptor, the family of receptors that includes cannabinoid, opioid, and several serotonin receptor subtypes.) GPR3 and GPR6 are both known as “orphan receptors” because the principal endogenous compounds that bind to these receptors have yet to be identified. Some of the potential therapeutic effects of CBD for Alzheimer’s disease, Parkinson’s disease and schizophrenia may be mediated by GPR3and GPR6.

Amyloid beta plaque and tau protein tangles in the brain are hallmarks of Alzheimer’s dementia. Tim Karl from the Western Sydney University School of Medicine in Australia elaborated on CBD’s therapeutic potential for this neurodegenerative brain disease: “The phytocannabinoid cannabidiol possesses antioxidant, anti-inflammatory and neuroprotective properties and prevents amyloid beta-induced neuroinflammation, and tau hyperphosphorylation in vitro. CBD also reverses cognitive deficits of pharmacological amyloid beta models. Thus, CBD may offer therapeutic value for Alzheimer’s disease.”

Another receptor, known as GPR55, is inhibited by CBD. This is significant because preclinical research has linked GPR55 activation to several aberrant conditions, including colon cancer and Dravet Syndrome, a severe seizure disorder. By functioning as a GPR55 “antagonist,” CBD may confer a tumor-suppressing and anti-epileptic effect, although clinical studies have yet to confirm whether this mechanism of action is applicable to humans as well as animals.

At the 2017 ICRS conference, numerous presentations focused on other areas of cannabinoid science that do not involve CBD but are nonetheless relevant for cannabis clinicians and patients. Some highlights:

  • Chronic cannabis use: Carrie Cutler, assistant professor at Washington State University, provided a much-needed rejoinder to scientifically dubious assertions that chronic cannabis use during adolescence causes brain damage and significant detrimental effects on cognition and IQ. Her study found that after controlling for confounding variables no “significant effects of cannabis use were detected on … measures of memory or executive functioning” other than “modest problems with verbal free recall (i.e., remembering lists of items) and prospective memory (i.e, remembering to do things in the future).” A second study presented by Cutler drew attention to marijuana’s stress-reducing effects: “[C]hronic cannabis use is associated with a blunted stress response and a reduced reliance on top-down attentional control that does not cause overall cognitive performance to suffer.”
  • Addiction: Vincenzo Di Marzo, a leading cannabinoid scientist at the Institute of Biomolecular Chemistry in Naples, Italy, gave a fascinating presentation on the cessation of nicotine addiction among cigarette smokers who suffer a traumatic brain injury. Di Marzo identified an endogenous lipid molecule, N-oleoyol-glycine (OlGly), which activates a receptor on the membrane of the cell’s nucleus, thereby reducing the rewarding effects of nicotine and nicotine-dependence in mice. In a separate study of morphine withdrawal, Di Marzo and a team of international researchers concluded: “Oleoyl Glycine is a newly discovered endogenous cannabinoid-like compound that may have therapeutic potential in the treatment of addiction.”
  • Pain relief: Temple University scientists found that “cannabinoids used in combination with opioids have the potential to reduce the dose of opioids needed for analgesia.” Jenny L. Wiley, a scientist with RTI International in North Carolina, and her colleagues at Washington State University reported encouraging results regarding the use of THC as a prophylactic treatment for chemotherapy-induced peripheral neuropathy. “Preliminary data suggest that THC administered chronically during the course of paclitaxel treatment decreases the development of mechanical allodynia [heightened sensitivity to pain] in both male and female rats.”
  • Sleep: Gwen Wurm at the University of Miami reported that medical cannabis use is associated with a decrease in the use of prescription and over-the-counter sleep medications. Moreover, according Wurm’s poster, “There is a strong relationship between use of medical cannabis for sleep and for pain.”
  • The CB2 receptor: Tel Aviv University scientist Bitya Raphael identified an endogenous hormone H4(99-103) that activates the cannabinoid CB2 receptor, which regulates immune function, metabolic processes and the peripheral nervous system. This is the first study showing that an endogenous circulating peptide signals via the CB2 receptor. A poster presented by Makenzie Fulmer at East Tennessee State University described how CB2 receptor dysfunction increases plaque calcification in a mouse model of atherosclerosis.

There were many other significant presentations during the four-day ICRS conference in Montreal that warrant mention – too many to adequately address in this summary. Project CBD looks forward to further developments next year when the ICRS convenes again at Leiden University in the Netherlands.

 

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Kanye West sues Lloyd's insurers amid dispute over marijuana use - Financial Times

Google - Cannabis - Wed, 08/02/2017 - 09:21

Financial Times

Kanye West sues Lloyd's insurers amid dispute over marijuana use
Financial Times
A rambling performance in Sacramento, a string of cancelled tour dates and allegations of marijuana use have added up to a $10m lawsuit that pits one of the world's biggest celebrities against the centuries-old Lloyd's insurance market. Rap star Kanye ...
Kanye West sues insurance firm for $10m over cancelled tour and marijuana use claimsThe Guardian
Kanye West's tour insurer Lloyd's of London claims marijuana caused his mental breakdown in $10 million lawsuit as ...Daily Mail
Kanye West Files $10 Million Lawsuit Over Tour Canceled Due to His Mental BreakdownHollywood Reporter

all 233 news articles »
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Meadow is the Amazon of weed - TechCrunch

Google - Cannabis - Wed, 08/02/2017 - 09:11

TechCrunch

Meadow is the Amazon of weed
TechCrunch
Marijuana legalization is sweeping the nation, and The Green Rush is upon us. As pot sellers scramble to comply with complex regulations, one startup has built the full-stack of specialized commerce software they need. Meadow offers everything from an ...

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80 Years Ago Today: President Signs First Federal Anti-Marijuana Law

Alternet - Wed, 08/02/2017 - 08:32
Click here for reuse options! It's time to end 80 years of failure.

Eighty years ago today, on August 2, 1937, President Franklin Roosevelt signed House Bill 6385: the Marihuana Tax Act into law. The Act for the first time imposed federal criminal penalties on activities specific to the possession, production, and sale of cannabis.

Congress’ decision followed the actions of 29 states, beginning with Massachusetts in 1914, that had previously passed laws criminalizing the plant over the prior decades. It also followed years of ‘Reefer Madness,’ during which time politicians, bureaucrats (led primarily by Federal Bureau of Narcotics Director Harry Anslinger), reporters, and science editors continually proclaimed that marijuana use irreparably damaged the brain. A 1933 editorial in the Journal of Criminal Law and Criminology largely summarized the sentiment of the time, “If continued, the inevitable result is insanity, which those familiar with it describe as absolutely incurable, and, without exception ending in death.”

On April 14, 1937, Rep. Robert L. Doughton of North Carolina introduced HR 6385, which sought to stamp out the recreational use of marijuana by imposing a prohibitive federal tax on all cannabis-related activities. Members of Congress held only two hearings to debate the merits of the bill, which largely relied on the sensational testimony of Anslinger — who opined, ”This drug is entirely the monster Hyde, the harmful effect of which cannot be measured.” Over objections from the American Medical Association, whose representatives opposed the proposed federal ban, members of the House and Senate overwhelmingly approved the measure by voice votes.

President Franklin Roosevelt promptly signed the legislation into law and on October 1, 1937, the Marihuana Tax Act officially took effect — thus setting in motion the federal prohibition that continues to this day.

Tell Congress to end 80 years of failure. Click here to urge federal leadership to support The Marijuana Justice Act of 2017 in the US Senate and click here to support The Ending Federal Marijuana Prohibition Act of 2017 in the US House of Representatives.

 

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Looming legalization spurs 'massive interest' in marijuana retail opportunities in Calgary - CBC.ca

Google - Cannabis - Wed, 08/02/2017 - 03:31

CBC.ca

Looming legalization spurs 'massive interest' in marijuana retail opportunities in Calgary
CBC.ca
City council approved the new land-use bylaw definition in June of 2016 to accommodate businesses that provide information about cannabis. Unlike medical marijuana clinics, counselling services don't necessarily have a doctor on staff. "I think that ...

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Cannabis industry to province: Make room for made-in-Manitoba weed - CBC.ca

Google - Cannabis - Wed, 08/02/2017 - 02:01

CBC.ca

Cannabis industry to province: Make room for made-in-Manitoba weed
CBC.ca
Winnipeg's modest legal-cannabis industry wants the Progressive Conservative government to foster a made-in-Manitoba marijuana sector as the clock ticks down toward the legalization of recreational weed. Cannabis producers and retailers say Brian ...

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FL: Orlando News Videos - WFTV

Bot - Cannabis - Wed, 08/02/2017 - 00:56
wftv.com (US) [ ...] ... (Wed Aug 02 18:56:41 2017 PDT)
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OR: Portland woman arrested in connection with trafficking of a mino - KPTV - FOX 12

Bot - Cannabis - Wed, 08/02/2017 - 00:55
kptv.com (US) A man was arrested in the Home Depot parking lot at Mall 205 with 20 kilos of methamphetamine and 4 kilos of heroin. (Wed Aug 02 21:55:00 2017 PDT)
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OR: PD: 'Good Samaritan' shoots, kills suspect during armed robbery - KPTV - FOX 12

Bot - Cannabis - Wed, 08/02/2017 - 00:55
kptv.com (US) Phoenix police say the man was trying to steal OxycontinB from the store. (Wed Aug 02 21:55:00 2017 PDT)
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